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MYP_007302
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
12 amino acids
C71H126N24O16
Standard
Sequence
KRIVQRIKDFLR
Physicochemical Analysis
1571.91 Da
11.72
3.76
3.55
0.3133
-0.71
0.97
-0.52
31.95
121.67
0.0833
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
701.55
-4.44
26.0
20.0
57.0
111.0
1.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0273309 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
No cytotoxic effects on human cells till 63 mM
63000 μM
Hemolysis
PMID18818205 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18818205/
RECORD: Rec_0273571 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Listeria monocytogenes
PMID18818205 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18818205/
RECORD: Rec_0309314 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Staphylococcus aureus 710A
PMID18818205 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18818205/
RECORD: Rec_0321417 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Bio-Activity Profile
Antimicrobial Antiparasitic Anti-inflammatory
Escherichia coli K12
40 μM
MIC
PaperStructures of human host defense cathelicidin LL-37 and its smallest antimicrobial peptide KR-12 in lipid micelles
RECORD: Rec_0336440 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa
PMID18818205 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18818205/
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