Peptide Database

Peptide NameSLAY-screened peptide P3616

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC43H74N16O20

DescriptionStandard

        SSARDSSVNNV
    

Molecular Weight1135.14 Da

Isoelectric Point (pI)5.55

Net Charge (pH 7.0)-0.54

Net Charge (pH 7.4) -0.75

Charge Density (pH 7.0) -0.0490

GRAVY Index-0.73

Hydrophobic Moment 0.10

Boman Index-0.27

Instability Index61.62

Aliphatic Index 61.82

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 620.62

LogP -11.96

H-bond Donors 22.0

H-bond Acceptors 20.0

Rotatable Bonds 37.0

Heavy Atoms 79.0

Ring Count 0.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0298539 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/