Peptide Database

Peptide NameHBPM4, Polyphemusin I [R10K,Y14R,R15Y]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC108H164N36O21S4

DescriptionStandard

        RRWCFRVCYKGFCRYKCR
    

Molecular Weight2430.95 Da

Isoelectric Point (pI)10.10

Net Charge (pH 7.0)6.72

Net Charge (pH 7.4) 6.45

Charge Density (pH 7.0) 0.3731

GRAVY Index-0.80

Hydrophobic Moment 0.67

Boman Index-0.51

Instability Index64.18

Aliphatic Index 16.11

Aromaticity 0.2778

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 975.81

LogP -6.67

H-bond Donors 43.0

H-bond Acceptors 32.0

Rotatable Bonds 78.0

Heavy Atoms 169.0

Ring Count 6.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0396729 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetEscherichia coli UB1005

Activity4 μg/mL

MethodMIC

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