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MYP_007283
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Basic Information
HBPM4, Polyphemusin I [R10K,Y14R,R15Y]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C108H164N36O21S4
Standard
Sequence
RRWCFRVCYKGFCRYKCR
Physicochemical Analysis
2430.95 Da
10.10
6.72
6.45
0.3731
-0.80
0.67
-0.51
64.18
16.11
0.2778
8480.00
8730.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
975.81
-6.67
43.0
32.0
78.0
169.0
6.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0317007 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus
4 μg/mL
MIC
PMID15980369;11087404 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15980369/
RECORD: Rec_0317663 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
85 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/11087404/ PMID11087404 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11087404/
RECORD: Rec_0327771 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Achromobacter xylosoxidans
64 μg/mL
MIC
PMID15980369;11087404 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15980369/
RECORD: Rec_0335651 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0345274 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028s
0.5 μg/mL
MIC
PMID15980369;11087404 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15980369/
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