Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC329H551N91O89S6

DescriptionStandard

        MKLFLVLIILLFEVLTDGARLKKCFNNVTGYCRKKCKVGERYEIGCLSGKLRCANDEEEKKRVI
    

Molecular Weight7397.84 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)5.46

Net Charge (pH 7.4) 5.14

Charge Density (pH 7.0) 0.0853

GRAVY Index-0.05

Hydrophobic Moment 0.62

Boman Index-0.07

Instability Index20.36

Aliphatic Index 105.00

Aromaticity 0.0781

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2969.12

LogP -21.96

H-bond Donors 110.0

H-bond Acceptors 101.0

Rotatable Bonds 263.0

Heavy Atoms 515.0

Ring Count 5.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0173137 VERIFIED: NO

Provenance & Taxonomy

OrganismGorilla gorilla [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence