Peptide Database

Peptide NameSLAY-screened peptide P4551

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC113H160N24O27S

DescriptionStandard

        PCWGYLVLPRYSDFTKPLY
    

Molecular Weight2318.69 Da

Isoelectric Point (pI)8.54

Net Charge (pH 7.0)0.95

Net Charge (pH 7.4) 0.87

Charge Density (pH 7.0) 0.0498

GRAVY Index-0.13

Hydrophobic Moment 0.43

Boman Index0.16

Instability Index2.31

Aliphatic Index 76.84

Aromaticity 0.2632

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 797.71

LogP -2.03

H-bond Donors 30.0

H-bond Acceptors 29.0

Rotatable Bonds 65.0

Heavy Atoms 165.0

Ring Count 9.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0222207 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/