Peptide Database

Peptide NameProgonadoliberin-3

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC330H519N101O104S2

DescriptionStandard

        QHWSYGWLPGGKRSVGELEATIRMMGTGEVVSLPEEASAQTQERLRPYNVINDDSSHFDRKKRSPNK
    

Molecular Weight7629.40 Da

Isoelectric Point (pI)8.35

Net Charge (pH 7.0)0.95

Net Charge (pH 7.4) 0.62

Charge Density (pH 7.0) 0.0142

GRAVY Index-1.04

Hydrophobic Moment 0.54

Boman Index-0.21

Instability Index64.50

Aliphatic Index 56.72

Aromaticity 0.0746

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3350.18

LogP -38.59

H-bond Donors 117.0

H-bond Acceptors 109.0

Rotatable Bonds 254.0

Heavy Atoms 537.0

Ring Count 13.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0343912 VERIFIED: YES

Provenance & Taxonomy

OrganismDicentrarchus labrax [Animal]

FamilyProgonadoliberin

Tax ID13489

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour