Peptide Database

Peptide NamePancrelipase protease

Function Ontology

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length231 amino acids

Chemical FormulaC1060H1662N296O338S14

DescriptionStandard

        FPTDDDDKIVGGYTCAANSIPYQVSLNSGSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTIAAN
    

Molecular Weight24409.22 Da

Isoelectric Point (pI)7.00

Net Charge (pH 7.0)-0.00

Net Charge (pH 7.4) -0.63

Charge Density (pH 7.0) -0.0000

GRAVY Index-0.11

Hydrophobic Moment 0.55

Boman Index0.11

Instability Index31.71

Aliphatic Index 80.61

Aromaticity 0.0736

Extinction Coeff. Reduced 33920.00

Extinction Coeff. Oxidized 34670.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0260478 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyEnzyme

Tax ID9823

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideDisulfide-bonded therapeutic scaffold described in source text

Bio-Activity Profile

Function

Enzyme replacement

Half-LifePancrelipase acts locally in the GI tract and it is not absorbed in any significant amount thus, the elimination half-life is not relevant.74