Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC732H1154N214O215S7

DescriptionStandard

        MPKVQFTKRKETSQIFVHCSATKPSMDIGVREIAQWHKEQGWLAIGYHFVIRRDGTVEAGRDQDAVGSHVKGYNSTSVGVCLVGGIDAKGNPEANFTPQQMSALKGLLHELKGTYPKATIMAHHDVAPKACPSFDLQRWVRTGELVTSDRG
    

Molecular Weight16616.75 Da

Isoelectric Point (pI)9.05

Net Charge (pH 7.0)4.10

Net Charge (pH 7.4) 3.44

Charge Density (pH 7.0) 0.0271

GRAVY Index-0.42

Hydrophobic Moment 0.65

Boman Index-0.02

Instability Index38.74

Aliphatic Index 71.66

Aromaticity 0.0728

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6874.89

LogP -72.75

H-bond Donors 241.0

H-bond Acceptors 233.0

Rotatable Bonds 550.0

Heavy Atoms 1168.0

Ring Count 28.0

Amide Bonds 161.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0218637 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage 066053 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic