Peptide Database

Peptide Nameceliac sprue gluten epitope found in secalin

Function Ontology

Venom / Toxin ▸ General toxin ▸ Celiac toxic

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC53H72N12O14

DescriptionStandard

        PYPQQPFPQ
    

Molecular Weight1101.21 Da

Isoelectric Point (pI)5.95

Net Charge (pH 7.0)-0.04

Net Charge (pH 7.4) -0.10

Charge Density (pH 7.0) -0.0047

GRAVY Index-1.71

Hydrophobic Moment 0.26

Boman Index-0.07

Instability Index151.00

Aliphatic Index 0.00

Aromaticity 0.2222

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 405.26

LogP -2.79

H-bond Donors 11.0

H-bond Acceptors 14.0

Rotatable Bonds 27.0

Heavy Atoms 79.0

Ring Count 6.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0056747 VERIFIED: NO

Provenance & Taxonomy

OrganismSecale cereale [Plant]

FamilyGliadin-derived

Tax ID4565;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Celiac toxic

TargetDQ2-positive celiac patient polyclonal T-cell lines

MethodT cell assay

PaperShan L., Qiao S-W., Arentz-Hansen H., Molberg O., Gray G. M., Sollid L. M., Khosla C.. Identification and analysis of multivalent proteolytically resistant peptides from gluten: implications for celiac sprue. J. Proteome Res., 2005, 4, 1732-1741. PMID16212427 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16212427/

RECORD: Rec_0366720 VERIFIED: NO