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MYP_007137
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Basic Information
Brevinin-2SSb
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
40 amino acids
C199H319N53O56S2
Standard
Sequence
SLFSLIKAGAKFLGKNMLKQGPQYPACKVSKDSENVNWKS
Physicochemical Analysis
4414.11 Da
9.81
4.45
4.21
0.1112
-0.47
0.60
-0.03
33.90
70.75
0.1000
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1790.00
-17.98
61.0
63.0
151.0
310.0
7.0
44.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0340874 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Monkey COS-7 cells
88.5 % Killing
Killing
PMID32751229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751229/
RECORD: Rec_0354743 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
HepG2
95.3 %
Cytotoxicity
PaperPubMed PMID: 32751229 PMID32751229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751229/
RECORD: Rec_0357363 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 32751229 PMID32751229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751229/
RECORD: Rec_0369461 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Bacillus cereus JCM 2152
PMID32751229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751229/
RECORD: Rec_0404862 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Salmonella enterica JCM 1652
128 μg/mL
MIC
PMID32751229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751229/
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