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MYP_007137
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Basic Information
Brevinin-2SSb
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
40 amino acids
C199H319N53O56S2
Standard
Sequence
SLFSLIKAGAKFLGKNMLKQGPQYPACKVSKDSENVNWKS
Physicochemical Analysis
4414.11 Da
9.81
4.45
4.21
0.1112
-0.47
0.60
-0.03
33.90
70.75
0.1000
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1790.00
-17.98
61.0
63.0
151.0
310.0
7.0
44.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0049092 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human hepatocellular carcinoma HepG2
90-100 % Killing
Killing
PMID32751229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751229/
RECORD: Rec_0134828 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa JCM 6119
128 μg/mL
MIC
PMID32751229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751229/
RECORD: Rec_0143402 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Clavibacter michiganensis subsp. michiganensis MAFF 301254
16 μg/mL
MIC
PMID32751229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751229/
RECORD: Rec_0161663 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans JCM 2085
128 μg/mL
MIC
PMID32751229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751229/
RECORD: Rec_0171706 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Xanthomonas oryzae pv. oryzae MAFF 311018
8 μg/mL
MIC
PMID32751229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751229/
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