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MYP_007134
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Basic Information
DV4(419-447)
Antimicrobial
Antiviral
Antiviral ▸ Anti-Flavivirus ▸ Anti-Dengue virus
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Standard
29 amino acids
C142H208N34O40S
Standard
Sequence
AWDFGSVGGLFTSLGKAVHQVFGSVYTTM
Physicochemical Analysis
3063.44 Da
6.79
-0.12
-0.36
-0.0041
0.53
0.58
0.38
-2.67
73.79
0.1724
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1170.61
-11.01
42.0
42.0
95.0
217.0
7.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0030982 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Dengue 3 virus(DENV3):inhibition of infection in BHK-21 cells
6 μM
IC90
PaperPubMed PMID: 20881042 PMID20881042 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20881042/
RECORD: Rec_0056607 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 20881042 PMID20881042 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20881042/
RECORD: Rec_0094639 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Dengue 2 virus(DENV2):inhibition of infection in BHK-21 cells
6 μM
IC90
PaperPubMed PMID: 20881042 PMID20881042 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20881042/
RECORD: Rec_0107761 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-DENV Entry inhibition
Dengue 4 virus (DENV4) | BHK-21 cells
6 μM
IC90
Mammalian: 4.4 h; Yeast: >20 h; E. coli: >10 h
PaperPeptide inhibitors of flavivirus entry derived from the E protein stem. | Schmidt AG, Yang PL, Harrison SC. | J Virol. 2010 Dec;84(24):12549-54. | DOI:10.1128/JVI.01440-10 | PMID:20881042 PMID20881042 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20881042/
RECORD: Rec_0120886 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-DENV Entry inhibition
Dengue 3 virus (DENV3) | BHK-21 cells
6 μM
IC90
Mammalian: 4.4 h; Yeast: >20 h; E. coli: >10 h
PaperPeptide inhibitors of flavivirus entry derived from the E protein stem. | Schmidt AG, Yang PL, Harrison SC. | J Virol. 2010 Dec;84(24):12549-54. | DOI:10.1128/JVI.01440-10 | PMID:20881042 PMID20881042 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20881042/
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