Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2104H3242N636O588S17

DescriptionStandard

        MPAAPTCTWSFTGDRGDAGRPAPITGTPPCPWEGGGGLGRLGGELRTPLCAPQLALQPPGAAAPENPAAAAEQAALRRAPEEHQQAGGLPEAHASVPPARPLRCHRPLLAGPPGDHGGARGRQPQGGASAGLGGGGKCLGWGAQTDPGVHLSVRPSAQGEFFGVDRRWQSPFSPRPVGLPEAREPMLLLAVTEFVANSAAFVYFTAGALRRNISGEALPRRFPLQLRTKSLGVFSPQLQEHFPDLPMELHLSARRQPLLSCRPDALHGTLFGSAEAFVVLPNATRVPAFLLDIVSAWPQGAELGCWGPYWGPAGRCWALPGDAGTAPASPTSPLAAGRQRDGEADHHGEQAGGHRAADEVRPPPAPRWVRAPLGPPREAAPVLHLRPFPSLGPFHLLSPHPAPGSHPCPPSWCSEPGQVLSWSRSAGLGLPALPGSACPCPGGVGRGHSPHPCARC
    

Molecular Weight47399.26 Da

Isoelectric Point (pI)8.72

Net Charge (pH 7.0)6.91

Net Charge (pH 7.4) 5.58

Charge Density (pH 7.0) 0.0152

GRAVY Index-0.30

Hydrophobic Moment 0.63

Boman Index0.06

Instability Index67.23

Aliphatic Index 67.81

Aromaticity 0.0614

Extinction Coeff. Reduced 63480.00

Extinction Coeff. Oxidized 64355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0049101 VERIFIED: NO

Provenance & Taxonomy

OrganismAnser cygnoid [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria