Peptide Database

Peptide NameTP1[K1A, Y8A] (Derived from TP1)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC90H143N33O19S4

DescriptionStandard

        AWCFRVCARGICYRRCR
    

Molecular Weight2119.57 Da

Isoelectric Point (pI)9.88

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.51

Charge Density (pH 7.0) 0.2797

GRAVY Index0.00

Hydrophobic Moment 0.60

Boman Index-0.30

Instability Index23.17

Aliphatic Index 51.76

Aromaticity 0.1765

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 874.44

LogP -7.52

H-bond Donors 39.0

H-bond Acceptors 28.0

Rotatable Bonds 66.0

Heavy Atoms 146.0

Ring Count 4.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0393800 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configstapled cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Disulfide3-16; 7-12

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic

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