Peptide Database

Peptide NameLEAP-2

Function Ontology

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Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC192H323N65O59S6

DescriptionStandard

        MTPFWREVSLRRIGASCMDNSECTTRLCRKRRCSLSVAQE
    

Molecular Weight4678.41 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)3.47

Net Charge (pH 7.4) 3.19

Charge Density (pH 7.0) 0.0869

GRAVY Index-0.52

Hydrophobic Moment 0.55

Boman Index-0.30

Instability Index98.39

Aliphatic Index 58.50

Aromaticity 0.0500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2061.76

LogP -25.54

H-bond Donors 81.0

H-bond Acceptors 69.0

Rotatable Bonds 158.0

Heavy Atoms 322.0

Ring Count 4.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0142233 VERIFIED: YES

Provenance & Taxonomy

OrganismDasypus novemcinctus [Animal]

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)