Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length187 amino acids

Chemical FormulaC922H1481N261O246S9

DescriptionStandard

        PTALPAAQEPMLLLAVTEVLANSAAFTYFTAGALRRNISGNMLPRRFPLQLRTKSMGLFAPELQERYPDQPMELHLSARRQPLLSCRPNALHGTLFSSAEAFVVLPNATRIPAFLLNIDANVTGKPTISRNRLGGTVSLKGPLCLPRAGLRGLPVPQVKRLENMLKFGLWLFGVPWANSECCAHPVP
    

Molecular Weight20446.81 Da

Isoelectric Point (pI)10.35

Net Charge (pH 7.0)10.20

Net Charge (pH 7.4) 9.91

Charge Density (pH 7.0) 0.0545

GRAVY Index0.06

Hydrophobic Moment 0.60

Boman Index0.09

Instability Index58.45

Aliphatic Index 97.11

Aromaticity 0.0695

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7978.64

LogP -93.62

H-bond Donors 276.0

H-bond Acceptors 268.0

Rotatable Bonds 649.0

Heavy Atoms 1438.0

Ring Count 38.0

Amide Bonds 202.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0127232 VERIFIED: NO

Provenance & Taxonomy

OrganismChionis minor [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria