‹ ›
MYP_006916
← PREVIOUS NEXT → BACK
Basic Information
A12L/A20L/A23L
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
26 amino acids
C148H248N36O34
Standard
Sequence
KWKSFLKTFKSLKKTVLHTLLKLISS
Physicochemical Analysis
3075.77 Da
10.78
6.84
6.58
0.2631
0.02
0.69
0.01
0.03
116.15
0.1154
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1159.04
-6.31
43.0
42.0
109.0
218.0
5.0
25.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0024481 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Designed peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID21252288 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21252288/
RECORD: Rec_0036948 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
PeptideV13K
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
HeLa
2.2 μM
IC50
PaperStudies on mechanism of action of anticancer peptides by modulation of hydrophobicity within a defined structural framework PMID21252288 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21252288/
RECORD: Rec_0037652 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
PeptideV13K
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
B-16
4.6 μM
IC50
PaperStudies on mechanism of action of anticancer peptides by modulation of hydrophobicity within a defined structural framework PMID21252288 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21252288/
RECORD: Rec_0048472 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 84.6%, E 0.0%, T 0.0%, C 15.4% [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0049430 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa M2
500 μg/mL
MIC
PMID17158938 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17158938/
1 2 3 ... 5 NEXT LAST
Showing 5 records on this page · Page 1 of 5