Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length160 amino acids

Chemical FormulaC799H1208N184O242S10

DescriptionStandard

        QGIVYPGGNYSAPPFMAAPFTVPDQSDCMLYLAFSQYFFQTSSFAYYTAGAFNITIAEEVSRTCSYFNISTEIFGSIIPEVAQYSVTPYPVMLKLMATETPIISLQQDSFTLEIQGSMEVFAVLPDSSTQSLFTMSIAANTSIAVNIFDQKLMGSLCLNR
    

Molecular Weight17583.88 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-8.26

Net Charge (pH 7.4) -8.53

Charge Density (pH 7.0) -0.0516

GRAVY Index0.32

Hydrophobic Moment 0.56

Boman Index0.25

Instability Index55.98

Aliphatic Index 83.56

Aromaticity 0.1375

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6744.63

LogP -65.07

H-bond Donors 231.0

H-bond Acceptors 244.0

Rotatable Bonds 555.0

Heavy Atoms 1235.0

Ring Count 32.0

Amide Bonds 175.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0294240 VERIFIED: NO

Provenance & Taxonomy

OrganismNothocercus julius [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria