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MYP_006841
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Basic Information
H3
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Enzyme modulation ▸ Enzyme inhibition ▸ Infection inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
10 amino acids
C60H91N11O11S2
Standard
Sequence
WPFCLLLMAL
Physicochemical Analysis
1206.56 Da
5.52
-0.25
-0.47
-0.0250
2.17
0.11
0.79
59.86
166.00
0.2000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
332.22
3.12
12.0
13.0
34.0
84.0
4.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0308560 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral Hemolytic
human erythrocytes
PaperPubMed PMID: 26251517 PMID26251517 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26251517/
RECORD: Rec_0354471 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antiviral Infection inhibition
Inhibition of post-infection in Huh7.5.1 cells
1.54±0.73 μM
EC50
Mammalian: 2.8 h; Yeast: 3 min; E. coli: 2 min
PaperA p7 Ion Channel-derived Peptide Inhibits Hepatitis C Virus Infection in Vitro. | Hong W, Lang Y, Li T, Zeng Z, Song Y, Wu Y, Li W, Cao Z. | J Biol Chem. 2015 Sep 18;290(38):23254-63. | DOI:10.1074/jbc.M115.662452 | PMID:26251517 PMID26251517 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26251517/
RECORD: Rec_0372386 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral Hemolytic
PaperPubMed PMID: 26251517 PMID26251517 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26251517/
RECORD: Rec_0372991 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
Hepatitis C Virus(HCV):inhibition of viral infection in Huh7
PaperPubMed PMID: 26251517 PMID26251517 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26251517/
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