Peptide Database

Peptide NameBovine Beta-defensin 2

Function Ontology

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Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC181H308N64O46S7

DescriptionStandard

        VRSYLSCWGNRGICLLNRCPGRMRQIGTCLAPRVKCCR
    

Molecular Weight4341.24 Da

Isoelectric Point (pI)10.21

Net Charge (pH 7.0)7.67

Net Charge (pH 7.4) 7.37

Charge Density (pH 7.0) 0.2019

GRAVY Index-0.10

Hydrophobic Moment 0.65

Boman Index-0.17

Instability Index45.06

Aliphatic Index 79.47

Aromaticity 0.0526

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1807.74

LogP -20.16

H-bond Donors 73.0

H-bond Acceptors 61.0

Rotatable Bonds 142.0

Heavy Atoms 298.0

Ring Count 5.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0354062 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)