Peptide Database

Peptide NameGcg-XTEN 288

Function Ontology

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length319 amino acids

Chemical FormulaC1080H1597N333O590S

DescriptionStandard

        HSQGTFTSDYSKYLDSRRAQDFVQWLMNTGGEGSGEGSEGEGSEGSGEGEGSEGSGEGEGGSEGSEGEGGSEGSEGEGGSEGSEGEGSGEGSEGEGGSEGSEGEGSGEGSEGEGSEGGSEGEGGSEGSEGEGSGEGSEGEGGEGGSEGEGSEGSGEGEGSGEGSEGEGSEGSGEGEGSGEGSEGEGSEGSGEGEGSEGSGEGEGGSEGSEGEGSEGSGEGEGGEGSGEGEGSGEGSEGEGGGEGSEGEGSGEGGEGEGSEGGSEGEGGSEGGEGEGSEGSGEGEGSEGGSEGEGSEGGSEGEGSEGSGEGEGSEGSGEG
    

Molecular Weight28717.18 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-95.88

Net Charge (pH 7.4) -96.30

Charge Density (pH 7.0) -0.3006

GRAVY Index-1.46

Hydrophobic Moment 0.66

Boman Index-0.07

Instability Index32.18

Aliphatic Index 3.67

Aromaticity 0.0157

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0091674 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGlucagon

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermXTEN

Bio-Activity Profile

Function

Antihyperglycemic Metabolic regulation

Target10–12 hours

MethodSandwich ELISA

Half-LifeInjected subcutaneouly into cynomolgus monkeys, in vivo; 32400 s