Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC557H859N147O147S12

DescriptionStandard

        MEHGVLGKLSVSFHAKLANKVFATLSFICATKYILGDHRFGPCLPRPCVNVFLGNTLNPTLLLVVTAAENEAASFPWSCSSLNGQCRNVCLPHEMFFGPLGCGKGFMCCVSHFL
    

Molecular Weight12351.46 Da

Isoelectric Point (pI)8.43

Net Charge (pH 7.0)2.85

Net Charge (pH 7.4) 2.24

Charge Density (pH 7.0) 0.0250

GRAVY Index0.46

Hydrophobic Moment 0.64

Boman Index0.24

Instability Index14.47

Aliphatic Index 88.07

Aromaticity 0.1053

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4579.52

LogP -40.95

H-bond Donors 164.0

H-bond Acceptors 167.0

Rotatable Bonds 391.0

Heavy Atoms 863.0

Ring Count 25.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0339069 VERIFIED: NO

Provenance & Taxonomy

OrganismOryzias sinensis [Animal]

FamilyDefensin

Tax ID183150

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal