Peptide Database

Peptide NameCRS1C-3 (Defensin; alpha; 39)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length116 amino acids

Chemical FormulaC548H891N157O170S12

DescriptionStandard

        MKTLVLLSALALLAFQVQADPIKNTDEETKTGEQPEEEDQAVSVSFGGTEGSALQYVAQRRFPWCRKCPVCQKCQVCQKCPVCPTCPQCPKLPLCKERQNKSAITTQAPNTQHKGC
    

Molecular Weight12783.67 Da

Isoelectric Point (pI)8.30

Net Charge (pH 7.0)2.49

Net Charge (pH 7.4) 2.03

Charge Density (pH 7.0) 0.0215

GRAVY Index-0.47

Hydrophobic Moment 0.42

Boman Index-0.09

Instability Index46.70

Aliphatic Index 64.74

Aromaticity 0.0431

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5277.38

LogP -61.20

H-bond Donors 184.0

H-bond Acceptors 186.0

Rotatable Bonds 422.0

Heavy Atoms 887.0

Ring Count 17.0

Amide Bonds 131.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0130574 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic