Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC546H888N150O163S3

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRIHVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWSIRTWMFKDSGRGTVHISKVFVTAIFTTPLDKRGPTSISLTSCRTTSGDVDIKLNGKT
    

Molecular Weight12257.99 Da

Isoelectric Point (pI)9.74

Net Charge (pH 7.0)5.21

Net Charge (pH 7.4) 4.97

Charge Density (pH 7.0) 0.0457

GRAVY Index0.02

Hydrophobic Moment 0.54

Boman Index0.10

Instability Index15.93

Aliphatic Index 95.70

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4997.81

LogP -55.27

H-bond Donors 180.0

H-bond Acceptors 174.0

Rotatable Bonds 406.0

Heavy Atoms 862.0

Ring Count 17.0

Amide Bonds 118.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0353747 VERIFIED: NO

Provenance & Taxonomy

OrganismErythrocercus mccallii [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria