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MYP_006687
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Basic Information
Cycloviolacin O25
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Insecticidal/Pest control ▸ Insecticidal activity
Standard
31 amino acids
C148H224N36O43S6
Standard
Sequence
DIFCGETCAFIPCITHVPGTCSCKSKVCYFN
Physicochemical Analysis
3387.97 Da
6.70
-0.21
-0.56
-0.0068
0.54
0.32
0.24
15.14
59.68
0.1290
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1238.53
-12.49
48.0
50.0
103.0
233.0
7.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0083337 VERIFIED: YES
Provenance & Taxonomy
Viola odorata [Plant]
97441
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
PaperA novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability. PMID16872274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16872274/
RECORD: Rec_0087823 VERIFIED: YES
Provenance & Taxonomy
Viola odorata [Plant]
Cyclotide
97441
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Insecticidal Enzymatic-digestion
PaperA novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability PMID16872274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16872274/
RECORD: Rec_0090848 VERIFIED: YES
Provenance & Taxonomy
Viola odorata [Plant]
Cyclotide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0101238 VERIFIED: NO
Provenance & Taxonomy
Viola odorata [Plant]
Cyclotide
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID16872274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16872274/
RECORD: Rec_0372513 VERIFIED: YES
Provenance & Taxonomy
Viola odorata [Plant]; Insecta [Animal]
33090; 50557
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID16872274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16872274/
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