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MYP_006676
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Basic Information
Antifungal peptide 2 (EAFP2; Plant defensin)
Antimicrobial
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
41 amino acids
C163H259N57O53S10
Standard
Sequence
QTCASRCPRPCNAGLCCSIYGYCGSGAAYCGAGNCRCQCRG
Physicochemical Analysis
4185.80 Da
8.62
3.66
3.30
0.0892
-0.07
0.53
-0.03
3.37
31.22
0.0732
4470.00
5095.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1771.31
-28.75
73.0
67.0
129.0
283.0
5.0
44.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0261757 VERIFIED: YES
Provenance & Taxonomy
Eucommia ulmoides [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
35-37
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium oxysporum (IC50=94 μg/ml) and Colletotrichum gossypii
56 μg/mL
IC50
PaperPubMed PMID: 12067732 | PubMed PMID: 15363789 | PubMed PMID: 15147184 PMID12067732;15363789;15147184 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12067732/
RECORD: Rec_0267939 VERIFIED: YES
Provenance & Taxonomy
Eucommia ulmoides [Plant]
Hevein, Chitin-binding
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Pyroglutamate
disulfide bond reported, sites not specified
N-terminal pyroglutamate
Bio-Activity Profile
Antimicrobial Antifungal
Verticillium dahliae
PaperPubMed PMID 12067732 | PubMed PMID 15147180 PMID12067732;15147180 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12067732/
RECORD: Rec_0276924 VERIFIED: YES
Provenance & Taxonomy
Eucommia ulmoides [Plant]
Hevein, Chitin-binding
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Pyroglutamate
disulfide bond reported, sites not specified
N-terminal pyroglutamate
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium moniliforme
18 μg/mL
IC50
PaperPubMed PMID 12067732 | PubMed PMID 15147180 PMID12067732;15147180 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12067732/
RECORD: Rec_0283675 VERIFIED: YES
Provenance & Taxonomy
Eucommia ulmoides [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
35-37
Bio-Activity Profile
Antimicrobial Antifungal
Verticillium dahliae
PaperPubMed PMID: 12067732 | PubMed PMID: 15363789 | PubMed PMID: 15147184 PMID12067732;15363789;15147184 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12067732/
RECORD: Rec_0312108 VERIFIED: YES
Provenance & Taxonomy
Eucommia ulmoides [Plant]
Hevein, Chitin-binding
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Pyroglutamate
disulfide bond reported, sites not specified
N-terminal pyroglutamate
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium oxysporum
56 μg/mL
IC50
PaperPubMed PMID 12067732 | PubMed PMID 15147180 PMID12067732;15147180 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12067732/
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