Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC543H881N149O162S4

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRMHVTAVELPSASISLLPASGIKLVIGNASLTIDMNWNIRTWMFKGTGRGKVHISKVFVTAIFSTPLDNTGPTSISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12216.96 Da

Isoelectric Point (pI)9.74

Net Charge (pH 7.0)5.21

Net Charge (pH 7.4) 4.97

Charge Density (pH 7.0) 0.0457

GRAVY Index0.03

Hydrophobic Moment 0.49

Boman Index0.12

Instability Index20.29

Aliphatic Index 94.04

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4964.56

LogP -55.53

H-bond Donors 177.0

H-bond Acceptors 174.0

Rotatable Bonds 405.0

Heavy Atoms 858.0

Ring Count 17.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0111694 VERIFIED: NO

Provenance & Taxonomy

OrganismMohoua ochrocephala [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria