Peptide Database

Peptide NamePeptide 22

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC103H169N35O24

DescriptionStandard

        RPDKPRPYLPSPRPPRPVR
    

Molecular Weight2281.66 Da

Isoelectric Point (pI)11.83

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.55

Charge Density (pH 7.0) 0.2505

GRAVY Index-1.94

Hydrophobic Moment 0.51

Boman Index-0.62

Instability Index89.38

Aliphatic Index 35.79

Aromaticity 0.0526

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 930.08

LogP -8.26

H-bond Donors 31.0

H-bond Acceptors 29.0

Rotatable Bonds 61.0

Heavy Atoms 162.0

Ring Count 9.0

Amide Bonds 18.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0236905 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-Term1-Amino cyclohexyl carboxylic acid

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus DSM 6247

Activity128 μg/mL

MethodMIC

RECORD: Rec_0262476 VERIFIED: YES