Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length108 amino acids

Chemical FormulaC530H857N159O156S7

DescriptionStandard

        AWRRMPPKCWKDNLGRCRVRCRGDERYIYLCRNKANCCILLTLAEDQSAHPKPTSVHPENVTWKNTSISPTTRYIDDITLDKTSIGTPTNVAGIGKALNLTVITPTHP
    

Molecular Weight12176.90 Da

Isoelectric Point (pI)9.35

Net Charge (pH 7.0)7.00

Net Charge (pH 7.4) 6.55

Charge Density (pH 7.0) 0.0648

GRAVY Index-0.54

Hydrophobic Moment 0.65

Boman Index-0.11

Instability Index27.67

Aliphatic Index 76.76

Aromaticity 0.0556

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5075.81

LogP -55.61

H-bond Donors 184.0

H-bond Acceptors 173.0

Rotatable Bonds 390.0

Heavy Atoms 852.0

Ring Count 21.0

Amide Bonds 115.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0110208 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0143177 VERIFIED: NO