Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length387 amino acids

Chemical FormulaC1959H3128N500O566S18

DescriptionStandard

        MKLSIEIQREAKVPFTQIKIIEGTTTLTAEGVTATITVRMNQNPQGHLNVEIPRDNCTIKADTIRTTSSGLTGFLLDSLQYFRLYLYLFNDKICPALQPMINNKLKDLPMMSTVYEDHQLDLDYSLSSDIEVTSSSLDISFKGLLSVHGKAVDPGSIRPGREPVFTETNKMVYVGISEFFFNGAAMAIYKSGPFEFNVPEMEGLLVGLGQKIMEIKPGPWTAELIEAPIIEISNDDLSATAYFKAQRKAKLNGFLMTCRFKMDIEFKERLLIMNIQEPKCKEKAGKIKGKFLVRRQCSNRFTSISLYQQIFIIIIIIIIITCVSLFVQAFLVNVFHERITKSLVKEIPIPLPAELSLINATNQFEEGYLVVGGSLTFNPQNSSNAGG
    

Molecular Weight43317.97 Da

Isoelectric Point (pI)6.91

Net Charge (pH 7.0)-0.16

Net Charge (pH 7.4) -0.77

Charge Density (pH 7.0) -0.0004

GRAVY Index0.05

Hydrophobic Moment 0.75

Boman Index0.11

Instability Index30.87

Aliphatic Index 100.52

Aromaticity 0.0879

Extinction Coeff. Reduced 20400.00

Extinction Coeff. Oxidized 20775.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0392470 VERIFIED: NO

Provenance & Taxonomy

OrganismOreochromis niloticus (Not founde tilapia) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria