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MYP_006592
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Basic Information
L-15
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
not Standard
22 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
RXRPRPYSPRPTSHPRPIRVXX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
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0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0149762 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 2; non-canonical residue code at 21; non-canonical residue code at 22; peptide is the all-L and all-D form, respectively, lower case letters denote D form. suffix m = conjugate containing a control PNA with two mismatched (interchanged) nucleobases, X = 6-aminohexanoic acid = H2N-(CH2)5COOH residue, Anti-acpP: B= PNA2301 = H-CTCATACTCT-NH2, Mismatch: J = PNA3961 = H-CTCTTACACT-NH2, O = Mal= polar maleimide linker, Z = eg1= Ethylene glycol moeity
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae NMI 2697/14
32 μg/mL
MIC
PMID30807888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30807888/
RECORD: Rec_0156819 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 2; non-canonical residue code at 21; non-canonical residue code at 22; peptide is the all-L and all-D form, respectively, lower case letters denote D form. suffix m = conjugate containing a control PNA with two mismatched (interchanged) nucleobases, X = 6-aminohexanoic acid = H2N-(CH2)5COOH residue, Anti-acpP: B= PNA2301 = H-CTCATACTCT-NH2, Mismatch: J = PNA3961 = H-CTCTTACACT-NH2, O = Mal= polar maleimide linker, Z = eg1= Ethylene glycol moeity
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli NMI 5428/11
1 μg/mL
MIC
PMID30807888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30807888/
RECORD: Rec_0179067 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 2; non-canonical residue code at 21; non-canonical residue code at 22; peptide is the all-L and all-D form, respectively, lower case letters denote D form. suffix m = conjugate containing a control PNA with two mismatched (interchanged) nucleobases, X = 6-aminohexanoic acid = H2N-(CH2)5COOH residue, Anti-acpP: B= PNA2301 = H-CTCATACTCT-NH2, Mismatch: J = PNA3961 = H-CTCTTACACT-NH2, O = Mal= polar maleimide linker, Z = eg1= Ethylene glycol moeity
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 29213
64 μg/mL
MIC
PMID30807888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30807888/
RECORD: Rec_0185511 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 2; non-canonical residue code at 21; non-canonical residue code at 22; peptide is the all-L and all-D form, respectively, lower case letters denote D form. suffix m = conjugate containing a control PNA with two mismatched (interchanged) nucleobases, X = 6-aminohexanoic acid = H2N-(CH2)5COOH residue, Anti-acpP: B= PNA2301 = H-CTCATACTCT-NH2, Mismatch: J = PNA3961 = H-CTCTTACACT-NH2, O = Mal= polar maleimide linker, Z = eg1= Ethylene glycol moeity
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli NMI 3548/14
1-2 μg/mL
MIC
PMID30807888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30807888/
RECORD: Rec_0217154 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 2; non-canonical residue code at 21; non-canonical residue code at 22; peptide is the all-L and all-D form, respectively, lower case letters denote D form. suffix m = conjugate containing a control PNA with two mismatched (interchanged) nucleobases, X = 6-aminohexanoic acid = H2N-(CH2)5COOH residue, Anti-acpP: B= PNA2301 = H-CTCATACTCT-NH2, Mismatch: J = PNA3961 = H-CTCTTACACT-NH2, O = Mal= polar maleimide linker, Z = eg1= Ethylene glycol moeity
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
64 μg/mL
MIC
PMID30807888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30807888/
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