Peptide Database

Peptide NameYunA signal peptide

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory enzyme production ▸ Cutinase secretion

Biotechnology / Production and expression ▸ Secretory expression optimization

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC200H323N45O46S4

DescriptionStandard

        MITDIFKPGCRKLCVFNMKGDYFVKVLLSALLLLLFA
    

Molecular Weight4222.24 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)2.48

Net Charge (pH 7.4) 2.22

Charge Density (pH 7.0) 0.0670

GRAVY Index1.08

Hydrophobic Moment 0.73

Boman Index0.33

Instability Index-6.07

Aliphatic Index 134.32

Aromaticity 0.1351

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1446.49

LogP -3.65

H-bond Donors 52.0

H-bond Acceptors 53.0

Rotatable Bonds 141.0

Heavy Atoms 295.0

Ring Count 6.0

Amide Bonds 37.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0108551 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilySec signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Cutinase secretion

TargetBacillus subtilis TEB1030

MethodSecretion phenotype assay

PaperBrockmeier U, Caspers M, Freudl R, et al. Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria[J]. Journal of Molecular Biology, 2006, 362(3): 393-402. PMID16930615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16930615/