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MYP_006560
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Basic Information
hBD-2c
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
19 amino acids
C95H157N29O24S2
Standard
Sequence
FCPRRYKQIGTGLPGTKCK
Physicochemical Analysis
2153.57 Da
10.06
4.74
4.50
0.2493
-0.80
0.56
-0.23
50.99
41.05
0.1053
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
875.18
-8.89
33.0
31.0
70.0
150.0
4.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0098355 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
2-18
Bio-Activity Profile
Antimicrobial
Escherichia coli (LC 19 uM). LC=lethal concentration. Antimicrobial robustness: NaCl-insensitive:Escherichia coli (150 mM); MgCl2-sensitive:Escherichia coli (2.5 mM)
PaperHuman-beta-defensins-1-3 and analogs do not require proton motive force for antibacterial activity against Escherichia coli.
RECORD: Rec_0130460 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ftsEX[LC = 19 microM
PMID16860904;18809937;23980689;29682907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16860904/
RECORD: Rec_0135142 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus NCTC 8530
PMID16860904;18809937;23980689;29682907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16860904/
RECORD: Rec_0152866 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus NCTC 8530
12 μg/mL
MBC
PMID16860904;18809937;23980689;29682907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16860904/
RECORD: Rec_0224996 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus NCTC 8530[LC = 23 microM
PMID16860904;18809937;23980689;29682907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16860904/
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