Peptide Database

Peptide NameTheromacin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length97 amino acids

Chemical FormulaC459H726N138O139S13

DescriptionStandard

        MELKSGLSILLCFGICIAVINAGCFEDWSRCSPSTSRGTGVLWRDCDSYCKVCFKADRGECFDSPSLNCPQRLPNNKQCRCINARTAKDNRNPTCWA
    

Molecular Weight10818.36 Da

Isoelectric Point (pI)8.49

Net Charge (pH 7.0)3.39

Net Charge (pH 7.4) 2.98

Charge Density (pH 7.0) 0.0350

GRAVY Index-0.28

Hydrophobic Moment 0.54

Boman Index-0.08

Instability Index46.59

Aliphatic Index 63.40

Aromaticity 0.0825

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 18740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4492.37

LogP -53.79

H-bond Donors 169.0

H-bond Acceptors 156.0

Rotatable Bonds 352.0

Heavy Atoms 749.0

Ring Count 16.0

Amide Bonds 105.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0115339 VERIFIED: YES

Provenance & Taxonomy

OrganismTheromyzon tessulatum [other]

FamilyMacin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Non-hemolytic

TargetEscherichia coli

RECORD: Rec_0122382 VERIFIED: YES