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MYP_006497
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Basic Information
Hemoglobin beta chain [064-069]
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
6 amino acids
C30H57N9O8
Standard
Sequence
GKKVLQ
Physicochemical Analysis
671.83 Da
10.00
1.76
1.55
0.2930
-0.62
0.75
-0.20
34.37
113.33
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
303.95
-2.32
10.0
10.0
25.0
47.0
0.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0041614 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
1.9 μM
IC50
RECORD: Rec_0132980 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0239678 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
1.9
IC50
PaperMito K., Fujii M., Kuwahara M., Matsumura N., Shimizu T., Sugano S., Karaki H.. Antihypertensive effect of angiotensin I-converting enzyme inhibitory peptides derived from hemoglobin. Eur. J. Pharmacol., 304, 93-98.
RECORD: Rec_0241475 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
1.9 μM
IC50
PaperAntihypertensive effect of angiotensin I-converting enzyme inhibitory peptides derived from hemoglobin PMID8813589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8813589/
RECORD: Rec_0296923 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
ACE
1.9 μM
IC50
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