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MYP_006451
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Basic Information
Glucagon
Hormonal / Endocrine ▸ Hormone peptide
Metabolic
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Metabolic ▸ Glucose metabolism ▸ Antidiabetic ▸ Antihypoglycemic
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Therapeutic / Biomedical activity ▸ Enzyme replacement therapy
Standard
29 amino acids
C153H225N43O49S
Standard
Sequence
HSQGTFTSDYSKYLDSRRAQDFVQWLMNT
Physicochemical Analysis
3482.75 Da
6.75
-0.15
-0.41
-0.0053
-0.99
0.66
-0.18
56.03
40.34
0.1724
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1538.74
-17.94
55.0
51.0
113.0
246.0
7.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004909 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Glucagon
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Metabolic
PMID5102927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5102927/
RECORD: Rec_0045900 VERIFIED: YES
Provenance & Taxonomy
Saimiri sciureus [Animal]
Glucagon
9521
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
2:Phosphoserine
Bio-Activity Profile
Hormone Endocrine Metabolic regulation Physiological regulation
Experimental: <10 minutes; /600 seconds; Mammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Glucagon (Saimiri sciureus): PMID 2263627##20418955 PMID2263627;20418955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2263627/
RECORD: Rec_0049638 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Glucagon
9913
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
2:Phosphoserine
Bio-Activity Profile
Hormone Endocrine Metabolic regulation Physiological regulation Receptor modulation
Experimental: <10 minutes; /600 seconds; Mammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Glucagon (Bos taurus): PMID 5102927##20418955 PMID5102927;20418955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5102927/
RECORD: Rec_0052415 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
glucagon family
9606; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
2-Ser: Phosphoserine
Bio-Activity Profile
Hormone glucagon family
PaperPDB 2G49 structural record; X-ray; 2.50 A; chain C/D; residues 1-29
RECORD: Rec_0071300 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Glucagon
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Metabolic
PMID11946536 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11946536/
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