Peptide Database

Peptide NameRanibizumab

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard StatusStandard

Sequence Length231 amino acids

Chemical FormulaC1123H1695N289O343S7

DescriptionStandard

        EVQLVESGGGLVQPGGSLRLSCAASGYDFTHYGMNWVRQAPGKGLEWVGWINTYTGEPTYAADFKRRFTFSLDTSKSTAYLQMNSLRAEDTAVYYCAKYPYYYGTSHWYFDVWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHL
    

Molecular Weight24956.66 Da

Isoelectric Point (pI)8.52

Net Charge (pH 7.0)3.22

Net Charge (pH 7.4) 2.67

Charge Density (pH 7.0) 0.0139

GRAVY Index-0.23

Hydrophobic Moment 0.58

Boman Index0.10

Instability Index42.01

Aliphatic Index 66.62

Aromaticity 0.1255

Extinction Coeff. Reduced 55350.00

Extinction Coeff. Oxidized 55600.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0176150 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Escherichia coli [Bacterium]

FamilyMonoclonal antibody

Tax ID9606;562

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory

Half-LifeApproximately 9 days.