Peptide Database

Peptide NameSLAY-screened peptide P3327

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC96H135N25O33

DescriptionStandard

        NGDPSQFSNPAHFIAVYSDT
    

Molecular Weight2167.25 Da

Isoelectric Point (pI)4.20

Net Charge (pH 7.0)-2.15

Net Charge (pH 7.4) -2.41

Charge Density (pH 7.0) -0.1076

GRAVY Index-0.54

Hydrophobic Moment 0.36

Boman Index0.09

Instability Index4.95

Aliphatic Index 44.00

Aromaticity 0.1500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 932.34

LogP -12.28

H-bond Donors 30.0

H-bond Acceptors 32.0

Rotatable Bonds 63.0

Heavy Atoms 154.0

Ring Count 6.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0149168 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/