Peptide Database

Peptide NameArdiscretin (PT-Arthr-beta* NaTx2.1) (Toxin TdNa4)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC427H645N105O115S13

DescriptionStandard

        MKGMIMLISCLMLIDVVVESKNGYIIEPKGCKYSCFWGSSTWCNRECKFKKGSSGYCAWPACWCYGLPDNVKIFDYYNNKCGK
    

Molecular Weight9506.17 Da

Isoelectric Point (pI)8.74

Net Charge (pH 7.0)4.41

Net Charge (pH 7.4) 4.03

Charge Density (pH 7.0) 0.0531

GRAVY Index-0.08

Hydrophobic Moment 0.40

Boman Index0.10

Instability Index42.42

Aliphatic Index 63.37

Aromaticity 0.1566

Extinction Coeff. Reduced 30940.00

Extinction Coeff. Oxidized 31440.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3530.88

LogP -27.18

H-bond Donors 132.0

H-bond Acceptors 133.0

Rotatable Bonds 310.0

Heavy Atoms 660.0

Ring Count 20.0

Amide Bonds 87.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0113715 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus discrepans [Animal]

FamilyLong (4 C-C) scorpion toxin; Sodium channel inhibitor; Beta subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Toxin Non-hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria

RECORD: Rec_0138092 VERIFIED: NO