Peptide Database

Peptide NameColicin-E9

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length127 amino acids

Chemical FormulaC472H727N151O167S2

DescriptionStandard

        MSGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIADIMAALKGPV
    

Molecular Weight11252.86 Da

Isoelectric Point (pI)5.97

Net Charge (pH 7.0)-2.15

Net Charge (pH 7.4) -2.57

Charge Density (pH 7.0) -0.0169

GRAVY Index-0.06

Hydrophobic Moment 0.36

Boman Index0.28

Instability Index25.12

Aliphatic Index 57.80

Aromaticity 0.0394

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4909.26

LogP -86.13

H-bond Donors 168.0

H-bond Acceptors 171.0

Rotatable Bonds 355.0

Heavy Atoms 792.0

Ring Count 18.0

Amide Bonds 135.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0075319 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli MS 84-1 [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli

MethodQualitative functional evidence