Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length154 amino acids

Chemical FormulaC762H1225N207O225S7

DescriptionStandard

        MQLSRKGLEAIKFFEGLKLEAYEDSAGIPTIGYGTIRIAGKPVKMGMKITAEQAEQYLLADVEKFVAAVNKAVKVPTSQNEFDALVSETYNIGITAMQDSTFIKRHNAGNKVGCAEAMQWWNKVTVKGKKVTSNGLKNRRRMEADIYLDSVYPK
    

Molecular Weight17110.58 Da

Isoelectric Point (pI)9.36

Net Charge (pH 7.0)5.59

Net Charge (pH 7.4) 5.25

Charge Density (pH 7.0) 0.0363

GRAVY Index-0.33

Hydrophobic Moment 0.69

Boman Index-0.01

Instability Index31.14

Aliphatic Index 81.10

Aromaticity 0.0844

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 19940.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7036.88

LogP -66.89

H-bond Donors 243.0

H-bond Acceptors 239.0

Rotatable Bonds 587.0

Heavy Atoms 1201.0

Ring Count 20.0

Amide Bonds 167.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0182109 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage VpaE1_ev035 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic