Peptide Database

Peptide NameAlpha-conotoxin EI

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC83H128N26O27S5

DescriptionStandard

        RDPCCYHPTCNMSNPQIC
    

Molecular Weight2082.39 Da

Isoelectric Point (pI)6.71

Net Charge (pH 7.0)-0.19

Net Charge (pH 7.4) -0.51

Charge Density (pH 7.0) -0.0107

GRAVY Index-0.72

Hydrophobic Moment 0.22

Boman Index-0.15

Instability Index44.02

Aliphatic Index 21.67

Aromaticity 0.0556

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 849.49

LogP -11.28

H-bond Donors 31.0

H-bond Acceptors 33.0

Rotatable Bonds 60.0

Heavy Atoms 141.0

Ring Count 5.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0246388 VERIFIED: YES

Provenance & Taxonomy

OrganismConus ermineus [Animal]

Familyconotoxin A superfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide4-10; 5-18

Other Mods3-Pro: 4-hydroxyproline

Bio-Activity Profile

Function

Toxin Venom conotoxin A superfamily Pathogenesis-associated Conotoxin

RECORD: Rec_0328291 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic