Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC374H633N97O109S7

DescriptionStandard

        MKLLLLLLTVTLLLAQVTPVTKCWGKSGRCRTTCKKSEVYYILCKTEAKCCVDPKYIPVRSKLTDTNTSLESTSAV
    

Molecular Weight8457.07 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)6.44

Net Charge (pH 7.4) 6.11

Charge Density (pH 7.0) 0.0847

GRAVY Index0.14

Hydrophobic Moment 0.61

Boman Index0.02

Instability Index17.12

Aliphatic Index 102.50

Aromaticity 0.0526

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3332.40

LogP -31.48

H-bond Donors 126.0

H-bond Acceptors 123.0

Rotatable Bonds 283.0

Heavy Atoms 587.0

Ring Count 8.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0011980 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Tax ID9544

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence