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MYP_006329
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Basic Information
Lantibiotic nukacin (Nukacin 3299) (Simulancin 3299)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
57 amino acids
C275H440N72O91S6
Standard
Sequence
MENSKVMKDIEVANLLEEVQEDELNEVLGAKKKSGVIPTVSHDCHMNSFQFVFTCCS
Physicochemical Analysis
6403.25 Da
4.71
-5.34
-5.72
-0.0936
-0.19
0.52
0.02
30.92
80.18
0.0526
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2644.74
-27.19
90.0
94.0
221.0
444.0
6.0
62.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0075346 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus simulans [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic
Gram-positive bacteria
PMID20627619 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20627619/
RECORD: Rec_0079587 VERIFIED: NO
Provenance & Taxonomy
Staphylococcus pasteuri [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic
Gram-positive bacteria
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A0M2NRT5/entry
RECORD: Rec_0184658 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus warneri [Bacterium]
Bacteriocin; Lantibiotic
Structure & Mods
ribosomally encoded bacteriocin peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic
Pediococcus spp.
PMID11193411;15322349;15737403;16233732;16957223 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11193411/
RECORD: Rec_0277030 VERIFIED: NO
Provenance & Taxonomy
Staphylococcus warneri [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 2023/0416797 A1 Evidence URLhttps://patents.google.com/patent/US20230416797A1/en PatentUS 2023/0416797 A1
RECORD: Rec_0320480 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus warneri [Bacterium]
Bacteriocin; Lantibiotic
Structure & Mods
ribosomally encoded bacteriocin peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic
Lactobacillus sakei
PMID11193411;15322349;15737403;16233732;16957223 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11193411/
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