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MYP_006315
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Basic Information
Pep-RTYM
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Flavivirus ▸ Anti-Dengue virus
Enzyme modulation ▸ Enzyme inhibition ▸ Infection inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
15 amino acids
C79H117N21O25S
Standard
Sequence
DHVTPDIAYNPRTYM
Physicochemical Analysis
1792.96 Da
5.21
-1.15
-1.41
-0.0768
-0.87
0.35
-0.08
20.99
52.00
0.1333
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
742.33
-6.61
25.0
26.0
51.0
126.0
5.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004382 VERIFIED: YES
Provenance & Taxonomy
Acacia catechu [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 33172110 PMID33172110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33172110/
RECORD: Rec_0031340 VERIFIED: YES
Provenance & Taxonomy
Acacia catechu [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
toxicity against Vero cells up to 1000 μM
1000 μM
Cytotoxicity
PaperPubMed PMID: 33172110 PMID33172110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33172110/
RECORD: Rec_0191053 VERIFIED: YES
Provenance & Taxonomy
Acacia catechu [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Dengue virus 2(DENV2):inhibition of viral infection in Vero cells
7.9 μM
IC50
PaperPubMed PMID: 33172110 PMID33172110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33172110/
RECORD: Rec_0271446 VERIFIED: YES
Provenance & Taxonomy
Acacia catechu [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 33172110 PMID33172110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33172110/
RECORD: Rec_0321825 VERIFIED: YES
Provenance & Taxonomy
Senegalia catechu [Plant]
138017
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-DENV Infection inhibition
Dengue virus 2(DENV2) | Vero cells
7.9 μM
IC50
Mammalian: 1.1 h; Yeast: 3 min; E. coli: >10 h
PaperSynthetic Bioactive Peptide Derived from the Asian Medicinal Plant Acacia catechu Binds to Dengue Virus and Inhibits Cell Entry. | Panya A, Sawasdee N, Songprakhon P, Tragoolpua Y, Rotarayanont S, Choowongkomon K, Yenchitsomanus PT. | Viruses. 2020 Nov 6;12(11):1267. | DOI:10.3390/v12111267 | PMID:33172110 PMID33172110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33172110/