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MYP_006302
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Basic Information
Rugosin-LK2
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
75 amino acids
C362H595N93O117S7
Standard
Sequence
MFTMKKSLLFLFFLGTISLSFCEGERSADEDDEGEMTEEEKRSIRDKGKTIAIDLAKSAGTGVLKTLMCKLDKSC
Physicochemical Analysis
8346.60 Da
5.09
-2.51
-2.80
-0.0335
-0.23
0.69
-0.04
30.39
76.80
0.0667
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3421.79
-33.64
124.0
122.0
298.0
579.0
5.0
74.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0043339 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Staphylococcus aureus (Gram-positive)
PMID23054029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23054029/
RECORD: Rec_0111141 VERIFIED: NO
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Rugosin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID23054029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23054029/
RECORD: Rec_0115256 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Bacillus subtilis (Gram-positive)
PMID23054029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23054029/
RECORD: Rec_0328579 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Escherichia coli (Gram-negative)
PMID23054029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23054029/
RECORD: Rec_0391400 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Pseudomonas aeruginosa (Gram-negative)
PMID23054029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23054029/
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