Peptide Database

Peptide NamePeptide1(ACE2 (21-43)[N13Q,A16V,D18E,L19I,F20Y,Y21W])

Function Ontology

Antimicrobial

Antiviral

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC150H222N36O48

DescriptionStandard

        IEEQAKTFLDKFQANTIHEVEEIYWQS
    

Molecular Weight3297.58 Da

Isoelectric Point (pI)4.41

Net Charge (pH 7.0)-4.14

Net Charge (pH 7.4) -4.41

Charge Density (pH 7.0) -0.1534

GRAVY Index-0.73

Hydrophobic Moment 0.53

Boman Index-0.02

Instability Index79.60

Aliphatic Index 75.93

Aromaticity 0.1481

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1393.51

LogP -10.51

H-bond Donors 46.0

H-bond Acceptors 45.0

Rotatable Bonds 111.0

Heavy Atoms 234.0

Ring Count 6.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0225283 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetSARS-CoV-2; HEK293T/ACE2 cells

MethodSARS-CoV-2 entry inhibition assay

RECORD: Rec_0310637 VERIFIED: YES