Peptide Database

Peptide NameFMRFamide-related peptide

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC59H85N17O15

DescriptionStandard

        GYPSRNYLRF
    

Molecular Weight1272.41 Da

Isoelectric Point (pI)9.99

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.1758

GRAVY Index-1.13

Hydrophobic Moment 0.52

Boman Index-0.27

Instability Index82.97

Aliphatic Index 39.00

Aromaticity 0.3000

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 544.01

LogP -4.52

H-bond Donors 20.0

H-bond Acceptors 17.0

Rotatable Bonds 37.0

Heavy Atoms 91.0

Ring Count 4.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0095832 VERIFIED: YES

Provenance & Taxonomy

OrganismHomarus americanus [Animal]

FamilyFMRFamide related peptide

Tax ID6706

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0291249 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0321126 VERIFIED: YES

Provenance & Taxonomy

OrganismHomarus americanus [Animal]

FamilyFMRFamide-related peptide

Tax ID6706

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

-

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour