Peptide Database

Peptide NameNeuropeptide S precursor

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Sleep regulation

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC329H539N91O90S2

DescriptionStandard

        YPVLSSKVPGKPDYFLILLSTCPARLEGSDGLAFLKPILEKTSMKRSFRNGVGSGVKKTSFRRAKQ
    

Molecular Weight7273.48 Da

Isoelectric Point (pI)10.35

Net Charge (pH 7.0)8.75

Net Charge (pH 7.4) 8.51

Charge Density (pH 7.0) 0.1325

GRAVY Index-0.29

Hydrophobic Moment 0.65

Boman Index-0.06

Instability Index46.59

Aliphatic Index 81.21

Aromaticity 0.0909

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2926.90

LogP -28.83

H-bond Donors 105.0

H-bond Acceptors 101.0

Rotatable Bonds 244.0

Heavy Atoms 512.0

Ring Count 11.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010066 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyNeuropeptide S precursor

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator Receptor modulation Immunomodulatory ACE inhibitory Sleep regulation Wake regulation

Half-LifeMammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min